Demystifying Oral Drug Absorption using the Finite Absorption Time Concept: Scientific and Regulator

Starts:  Feb 27, 2024 09:00 (ET)
Ends:  Mar 14, 2024 17:00 (ET)
Associated with  AAPS Community

Oral Drug Absorption and the Finite Absorption Time Concept

In the AAPS four-part webinar series, Demystifying Oral Drug Absorption using the Finite Absorption Time Concept: Scientific and Regulatory Applications, Panos Macheros, Ph.D., covers the development and application of modern oral drug absorption concepts.


These webinars are free to AAPS members and will be held over four days. Register for each session using the links below:

Tuesday, February, 27, 12:30pm-2pm ET

This presentation focuses on the widespread use of first-order kinetics in understanding oral drug absorption, highlighting the crucial role of the absorption rate constant.


Thursday, February 29, 12:30 pm-2pm ET

PBFTPK models integrate the drug properties of solubility and permeability from the biopharmaceutical classification system (BCS) with pharmacokinetics. Dr. Macheros demonstrates the potential of these models through detailed simulations of diverse pharmacokinetic time profiles.


Thursday, March 7, 12:30pm-2pm ET

The introduction of the Finite Absorption Time (F.A.T) caused a paradigm shift in oral pharmacokinetics. In this webinar, the novel aspects of bioavailability are described in terms of F.A.T.


Thursday, March 14, 12:30pm-2pm ET

The Wagner-Nelson and Loo-Riegelman methods, developed in the 1960s for modeling the percent of drug absorbed over time and for In Vitro-In Vivo Correlation (IVIVC), are re-evaluated in the context of the physiologically grounded F.A.T. concept.


Not an AAPS member? The only way to access this webinar live and in the eLearning archive is with an active AAPS membership. to receive immediate member benefits.

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