Oral Drug Absorption and the Finite Absorption Time Concept
In the AAPS four-part webinar series, Demystifying Oral Drug Absorption using the Finite Absorption Time Concept: Scientific and Regulatory Applications, Panos Macheros, Ph.D., covers the development and application of modern oral drug absorption concepts.
These webinars are free to AAPS members and will be held over four days. Register for each session using the links below:
The Collapse of the Oral Drug First-order Absorption Dogma: A New Era Based on the Finite Absorption
Tuesday, February, 27, 12:30pm-2pm ET
This presentation focuses on the widespread use of first-order kinetics in understanding oral drug absorption, highlighting the crucial role of the absorption rate constant.
The Development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) Models
Thursday, February 29, 12:30 pm-2pm ET
PBFTPK models integrate the drug properties of solubility and permeability from the biopharmaceutical classification system (BCS) with pharmacokinetics. Dr. Macheros demonstrates the potential of these models through detailed simulations of diverse pharmacokinetic time profiles.
Scientific & Regulatory Applications of F.A.T. Concept and PBFTK Models: Biovailability & Bioequiv
Thursday, March 7, 12:30pm-2pm ET
The introduction of the Finite Absorption Time (F.A.T) caused a paradigm shift in oral pharmacokinetics. In this webinar, the novel aspects of bioavailability are described in terms of F.A.T.
Scientific & Regulatory Applications of F.A.T. Concepts: Dissolution, IVIVC, Biowaivers
Thursday, March 14, 12:30pm-2pm ET
The Wagner-Nelson and Loo-Riegelman methods, developed in the 1960s for modeling the percent of drug absorbed over time and for In Vitro-In Vivo Correlation (IVIVC), are re-evaluated in the context of the physiologically grounded F.A.T. concept.
Not an AAPS member? The only way to access this webinar live and in the eLearning archive is with an active AAPS membership. Join today to receive immediate member benefits.