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  • 1.  Excipient sessions at PharmSci 360

    Community Leadership
    Posted 10-19-2023 21:56

    Presentations

    ON DEMAND

    ·        Prologue: "Grades" of Ancillary, Raw and Starting Materials and Excipients

    Prologue Speaker: @Allison Radwick  – USP

    ·        Prologue: Breaking Barriers for bRo5 Molecules: Formulation Strategies for Next-Generation Therapeutics

    Prologue Speaker: @Ketankumar Patel – St. John's University

    ·        Prologue: Excipients: It's Complicated

    Prologue Speaker: Chris Moreton, PhD (he/him/his) – FinnBritt Consulting

    ·        Prologue: Preformulation and Biopharmaceutical Support for Drug Delivery

    Prologue Speaker: @Andrei Blasko – Clearview Pharma Solutions LLC

    Monday, October 23, 2023

    Formulation and Delivery

    ·        9:00 AM – 10:00 AM ET Overcome Capping Challenges and Increase Tableting Speed in Direct Compression

    Location:360 Stage #1 Exhibit Hall West A4-B3

    Partner Presentation Speaker: @Talles Ernica – Roquette America Inc.

    ·        10:00 AM – 10:30 AM ET Novel Analytical Imaging and Dissolution Modeling

    Location:208 AB West

    Speaker: @Shawn Zhang – DigiM Solution LLC

    ·        10:00 AM – 10:30 AM ET Particle Engineering for High Concentration Protein Suspensions

    Location:209 AB West

    Speaker: @Erica Schlesinger – Seran Biosciences, LLC

    ·        9:00 AM – 9:30 AM ETAPI Co-Processing for Enhanced Solid Oral Dosages

    Location:205 AB West

    Speaker: @Rajesh Dave – NJIT

    ·        12:30 PM – 1:30 PM ET The Viscosity Reduction Platform: Enabling High-concentration and Low-viscosity Protein Formulations

    Location:360 Stage #2 Exhibit Hall West A4-B3

    Partner Presentation Speaker: Can Araman, PhD – MilliporeSigma

    ·        3:00 PM – 3:15 PM ET The Potential for a Ban on TiO2 (E171) Use in Pharmaceuticals and the Impact on Patients and the Industry

    Location:208 AB West

    Rapid Fire Speaker: @David Schoneker. – Black Diamond Regulatory Consulting/IPEC-Americas

    ·        3:45 PM – 4:00 PM ET Novel Strategies for Process-Related Impurity Clearance during Biologics Manufacturing

    Location:205 AB West

    Rapid Fire Speaker: @Aba Acquaah – Merck Research Laboratories

    Manufacturing & Analytical Characterization

    ·        9:00 AM – 9:30 AM ET Impact of Raw Materials Variation On Continuous Feeders Performance

    Location:206 AB West

    Speaker: @Sara Fathollahi – DFE Pharma

    ·        12:30 PM – 1:15 PM ET Calcium Carbonate as Alternative to Titanium Dioxide in Coatings

    Location: Spotlight Stage C Exhibit Hall West A4-B3

    Chalk Talk Presenter: @Giovanni Raspantini – MilliporeSigma a Business of Merck KGaA

    Tuesday, October 24, 2023

    Manufacturing & Analytical Characterization

    ·        9:00 AM – 9:30 AM ET Small Molecule Drug In Silico Crystal Structure and Property Predictions

    Location:205 AB West

    Speaker: @John Shelley – Schrodinger, LLC

    ·        10:00 AM – 10:30 AM ET Next Generation Lab-Scale Transport Validation: Fluid Behavior and Quality Impacts

    Location:205 AB West

    Speaker: @Florian Rosenthal – F. Hoffman - La Roche Ltd.

    ·       

    Formulation and Delivery

          9:00 AM – 11:00 AM ET Symposium: Enabling Excipients and Approaches for Advancing Formulation and Delivery 1

    Location:208 AB West

    Moderator: @Anette Mullertz – University of Copenhagen

    ·        9:00 AM – 9:30 AM ET Enabling Oral Absorption of Peptides By Self-Nanoemulsifying Drug Delivery Systems

    Location:208 AB West

    Speaker: @Anette Mullertz – University of Copenhagen

    ·        9:30 AM – 10:00 AM ET Environmentally-Responsive Hydrogel Excipient Broadly Enhances Oral Bioavailability of Insoluble Drugs

    Location:208 AB West

    Speaker: @Doug Godfrin – VeraMorph

    ·        10:00 AM – 10:30 AM ET High-Throughput Screening Workflow for Amorphous Solubility and Excipient Performance

    Location:208 AB West

    Speaker: @Yuchen Fan – Genentech Inc.

    ·        10:30 AM – 11:00 AM ET Understanding Surfactant-Protein Interactions in Mitigating Interface Induced Protein Particle Formation in Biotherapeutic Solutions Subjected to Interfacial Stresses

    Location:208 AB West

    Speaker: @Prajnaparamita Dhar – The University of Kansas

    ·        9:00 AM – 11:00 AM ET Symposium: Enabling Excipients and Approaches for Advancing Formulation and Delivery 2

    Location:209 AB West

    Moderator: @Haichen Nie – Teva Pharmaceuticals

    o   9:00 AM – 9:30 AM ET Strategic Overview of Complex Excipients in US Pharmacopeia With a Focus on Polysorbates and LG Polymer

    Speaker: @Otilia Koo – Bristol Myers Squibb

    o  9:30 AM – 10:00 AM ET Mechanistic Insights on Fogging in Lyophilized Formulations

    Speaker: @Navpreet Kaur – Sanofi

    o   10:00 AM – 10:30 AM ET Revisiting the Crucial Role of Amino Acids as Excipients in Protein-Based Drug Product Development

    Speaker: @Haichen Nie – Teva Pharmaceuticals

    o   10:30 AM – 11:00 AM ET Role of Excipients in Frozen and Freeze-Dried Protein Formulations

    Speaker: @Raj Suryanarayanan – College of Pharmacy/University of Minnesota

    ·        10:30 AM – 11:30 AM ETNew Generation of Digital Self-Serve Platforms Boost R&D Productivity

    Location:360 Stage #1 Exhibit Hall West A4-B3

    Partner Presentation Speaker: @Shahrzad Missaghi – Colorcon

    ·        12:30 PM – 1:15 PM ET Designing Pharmaceutical Materials for Extrusion Enabled Continuous Manufacturing

    Location: Spotlight Stage A Exhibit Hall West A4-B3

    Chalk Talk Presenter: @Thomas Durig – Ashland

    ·        1:30 PM – 2:30 PM ET Keynote: Excipient Taxonomy for the 21st Century: A Grand Challenge for the Pharmaceutical Sciences Community

    Location:209 AB West

    Keynote Speaker: @Bruno Hancock – Pfizer Inc.

    ·        1:30 PM – 2:30 PM ET Strategies to Reduce Nitrosamine Contamination of Drug Products

    Location:360 Stage #1 Exhibit Hall West A4-B3

    Partner Presentation Speaker: @Andreas Sauer – Shin-Etsu

    ·        2:30 PM – 3:30 PM ET Speaker Spotlight: The Value of USP Standards for Excipients Used in Medicines: Current and Future State

    Location: Spotlight Stage C Exhibit Hall West A4-B3

    Spotlight Speaker: @Catherine Sheehan – U.S. Pharmacopeia (USP)

    ·        2:30 PM – 3:30 PM ET Special Poster Collection

    Location: Poster Forum #7; Exhibit Hall West A4-B3

    Poster Collection Host: @Carl Allenspach

    ·        3:00 PM – 4:00 PM ET Rapid Fires: Enabling Excipients and Approaches for Advancing Formulation and Delivery 1

    Location:208 AB West

    Rapid Fire Moderator: Tzichi Ju, Ph.D. – AbbVie Inc.

    ·        3:00 PM – 3:15 PM ETORODS: a Novel Expandable Platform for in situ Drug Delivery

    Location:208 AB West

    Rapid Fire Speaker: @Matteo Cerea – Universita'  degli Studi di Milano

    ·        3:15 PM – 3:30 PM ET Novel Artemisinin-Containing Nanodrug for Leukemia Treatment

    Location:208 AB West

    Rapid Fire Speaker: @Noha Ghonim – University of Maryland Baltimore

    ·        3:30 PM – 3:45 PM ET Exploring Role of Lipidic and Phospholipidic Excipients for Dry-Powder Inhalers

    Location:208 AB West

    Rapid Fire Speaker: Nivedita Shetty, PhD (she/her/hers) – Genentech

    ·        3:45 PM – 4:00 PM ET Amorphous Dispersion Speciation: Impact of Polymer Chemistry and Molecular Weight

    Location:208 AB West

    Rapid Fire Speaker: @Wesley Tatum – Serán Bioscience

    ·        3:00 PM – 4:00 PM ET Rapid Fires: Enabling Excipients and Approaches for Advancing Formulation and Delivery 2

    Location:209 AB West

    Rapid Fire Moderator: @Michael Danquah– Chicago State University College of Pharmacy

    ·        3:00 PM – 3:15 PM ET Impact of Pneumatic Tube System Transportation on Biopharmaceutical Product Quality

    Location:209 AB West

    Rapid Fire Speaker: @Kashappa Goud Desai

    ·        3:15 PM – 3:30 PM ET Long-Acting Biodurable Implants: Fundamental Transport Properties to Complex Release Mechanisms

    Location:209 AB West

    Rapid Fire Speaker: @Angela Ren – University of Texas At Austin

    ·        3:30 PM – 3:45 PM ET Formulating Biologics for Oral Delivery – Considerations and Challenges

    Location:209 AB West

    Rapid Fire Speaker: @True Rogers

    ·        3:45 PM – 4:00 PM ET The Role of Saccharide Excipient Chemistry on Protein Particle Engineering

    Location:209 AB West

    Rapid Fire Speaker: @Amrit Paudel

    ·        4:00 PM – 5:00 PM ET AAPS Excipients Community Membership Meeting

    Location: Spotlight Stage A Exhibit Hall West A4-B3

    Community Leader: @Haichen Nie @Jin Zhao @Ketaki Patwardhan @Allison Radwick

    ·        5:00 PM – 6:00 PM ET Handbook of Pharmaceutical Excipients: Next Grand Challenges Continued (Invited guests only)

    Location: Challenger 41-42, Hyatt Regency Orlando

    Wednesday, October 25, 2023

    Formulation and Delivery

    ·        10:30 AM – 11:00 AM ET Application of Asymmetric Flow Field-Flow Fractionation (AFFF) and Capillary Electrophoresis (CE) for the Characterization of Liposomal Formulations

    Location:206 AB West

    Speaker: @Thilak Mudalige

    ·        3:00 PM – 4:00 PM ET Hot Topic: Novel Excipients in Biopharma: Balancing Innovation, Risk, and Need

    Location:308 AB West

    Hot Topic Speaker: @Joshua Katz

    Hot Topic Speaker: @Mary Krause

    Hot Topic Moderator: @Joshua Katz

    Hot Topic Speaker: @Andrea Hawe 

    Hot Topic Speaker: Can Araman, PhD – MilliporeSigma

    ·        3:15 PM – 3:30 PM ET Hierarchical Approach to Raw Material Variability in Drug Product Lifecycle

    Location:205 AB West

    Rapid Fire Speaker: @David Goldfarb

    ·        3:15 PM – 3:30 PM ET Characterization of Inhalation Drug Products Containing Spray-Dried Phospholipid Porous Particles

    Location:208 AB West

    Rapid Fire Speaker: @Yang Yang

    ·        3:45 PM – 4:00 PM ET Putting Lipids on the Map of 3D-Printable Filaments!

    Location:208 AB West

    Rapid Fire Speaker: @Moaaz Abdelhamid

    Manufacturing & Analytical Characterization

    ·        10:00 AM – 11:00 AM ET Development of Multiarticulate Formulations Using Innovative Excipients Through Algorithm-Based Tools

    Location: Spotlight Stage C Exhibit Hall West A4-B3

    Chalk Talk Presenter: @Nitin Swarnakar

    Chalk Talk Presenter: @Ramesh Muttavarapu

    ·        12:30 PM – 1:30 PM ET Special Poster Collection

    Location: Poster Forum #7; Exhibit Hall West A4-B3

    Poster Collection Host: @Carsten Ehrhardt

    ·        3:30 PM – 3:45 PM ET USP's Iterative Approach on Modern Analytical Methods for Polymeric Excipients

    Location:205 AB West

    Rapid Fire Speaker: @Peng Zhang



    ------------------------------
    Allison Radwick Ph.D.
    Sr Regulatory & Policy Comms Mgr
    USP
    Rockville MD
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
    ------------------------------


  • 2.  RE: Excipient sessions at PharmSci 360

    Community Leadership
    Posted 10-22-2023 11:59

    Really looking forward to it!



    ------------------------------
    Stacey Axler
    Community Manager
    AAPS
    Arlington VA
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
    ------------------------------



  • 3.  RE: Excipient sessions at PharmSci 360

    Posted 10-23-2023 08:50
    Thanks Allison for this excellent summary of excipient related talks. This will be very useful to all of us here at the AAPS meeting.

    Regards,

    Dave

    Sent from my mobile device.