Biomarkers and Precision Medicine Community (BPMC)

Please join for an Open Scientific Discussion (OSD) hosted by the AAPS Biomarkers and Precision Medicine (BPM) and Therapeutic Protein Immunogenicity (TPI) Communities on May 14th, 12 – 1 pm ET on the following topic:

Pharmacogenomics data from patients as biomarkers of Immunogenicity to Biologics

• Can patient HLA serve as a biomarker for immunogenicity risk?
• Predictive risk vs clinical data-related HLA association and challenges encountered
• Which parameter in in silico algorithms can correlate the best to observed clinical immunogenicity?
• Application of data mining approaches to support such associations and the development of suitable ML algorithms

Discussion Leaders:

• Surendran Rajendran (BMS)
• Andres Gutierrez (Epivax)

Moderated by: Vibha Jawa (BMS), Iris Qiu (Novartis)

Organized by: Carmen Fernández-Metzler (PharmaCadence) and Karen Quadrini (Prothena Biosciences)