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  • Posted in: AAPS Community

    Specifically, I'm interested in adhesion/cohesion of particles in inhalation products and the interface between the API and the (mostly polymeric) materials through/by which the particles pass upon actuation. ------------------------------ William Doub ...

  • Posted in: AAPS Community

    ​This is a surface phenomenon because of the hydrophobic nature of the Eudragit surface and spraying of water based Opadry coating solution.  One can visualize that the drops sprayed onto the surface do not spread and dry before spreading to a film causing ...

  • Posted in: AAPS Community

    Surface roughness could come due to many reasons including composition of the tablet (which is seldom considered as a possible reason). For example, using stearic acid (which has relatively low m.p.) as a lubricant makes the tablets 'softer' and ...

  • Posted in: AAPS Community

    Could you clarify about validation of area or any other validation ? ------------------------------ Dr. Pradum Ige Asso. Prof. R C Patel Institute of Pharmaceutical Education and Research Shirpur pradyumna_1978@rediffmail.com Disclaimer: Opinions expressed ...

  • Posted in: AAPS Community

    Dear team, I have a question about annual cleaning validation, we had more than 60 products, for each product, do we need to do annual cleaning validation, (or) there any other way to reduce the cleaning validation, instead of doing each product, ...

  • Posted in: AAPS Community

    Dear all, Thank you for your valuable inputs. I tried with slow spray rate too & I kept for eudragit L30D55 - 35 to 38 degree centigrade & for opdary I kept 40-45 degree centigrade & I gun distance also little far from tablet bed for opadry coating, ...

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