Webinar Presented By Dr. Yoon Yeo, Professor and Associate Department Head of Industrial and Physical Pharmacy at Purdue University.
Date: 2021 March 24 Wednesday at 12-1 pm ET
Albuminylation of Nanoparticles for Cancer Immunotherapy and Gene Delivery
Abstract:
Albumin is a promising surface modifier of nanoparticulate drug delivery systems Serving as a dysopsonin albumin can protect circulating nanoparticles (from the recognition and clearance by the mononuclear phagocytic system Albumin may also help transport the NPs to solid tumors based on the increased consumption by cancer cells and interactions with the tumor microenvironment Several studies have exploited the benefits of surface bound albumin to enhance NP delivery to tumors We have long been interested in modifying the NP surface by albumin either in the preparation or in situ for various purposes to increase the drug delivery to tumors after systemic administration to control the drug release kinetics for selective protection of normal cells, or to control the intracellular trafficking of NPs for enhancing gene delivery. This
webinar will highlight key outcomes of NP albuminylation in drug and siRNA delivery, based on our studies of nanocrystals, polymeric NP, and polyphenol nanocapsules.
How to join: https://bit.ly/36IVsHl (Zoom Meeting ID: 974 6926 7553; Passcode: 734026)