Pharmaceutical Discovery and Preclinical Development1

Hello PDPD Community!

An interesting article recently published by Wozniak et al in Nature: Enhanced mapping of small-molecule binding sites in cells - Nature Chemical Biology.

Incredibly powerful new tool to help identify binding sites on target proteins for small molecules - potentially a technique to identify binding sites for novel therapeutics across the proteome. As a small molecule medicinal chemist myself, this is rather exciting and intriguing - imagine the potential for novel small molecule modalities that could be identified and designed!

Can you share a pdf file for the paper?

Thanks,

Kilyoung

Hello PDPD Community!

An interesting article recently published by Wozniak et al in Nature: Enhanced mapping of small-molecule binding sites in cells - Nature Chemical Biology.

Incredibly powerful new tool to help identify binding sites on target proteins for small molecules - potentially a technique to identify binding sites for novel therapeutics across the proteome. As a small molecule medicinal chemist myself, this is rather exciting and intriguing - imagine the potential for novel small molecule modalities that could be identified and designed!

Hello PDPD Community!

An interesting article recently published by Wozniak et al in Nature: Enhanced mapping of small-molecule binding sites in cells - Nature Chemical Biology.

Incredibly powerful new tool to help identify binding sites on target proteins for small molecules - potentially a technique to identify binding sites for novel therapeutics across the proteome. As a small molecule medicinal chemist myself, this is rather exciting and intriguing - imagine the potential for novel small molecule modalities that could be identified and designed!

Hello PDPD Community!

An interesting article recently published by Wozniak et al in Nature: Enhanced mapping of small-molecule binding sites in cells - Nature Chemical Biology.

Incredibly powerful new tool to help identify binding sites on target proteins for small molecules - potentially a technique to identify binding sites for novel therapeutics across the proteome. As a small molecule medicinal chemist myself, this is rather exciting and intriguing - imagine the potential for novel small molecule modalities that could be identified and designed!