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Strategies for optimizing Neutralizing Antibody Assays

  • 1.  Strategies for optimizing Neutralizing Antibody Assays

    Community Leadership
    Posted 02-21-2023 09:29

    Next month, in the Neutralizing Antibody Assay Subteam, we will be discussing the just published work in the AAPS Journal on using a new method to overcome drug interference in Neutralizing Antibody assays (named Precipitation, Acid Dissociation and Biotin-drug as Assay Drug, PABAD). If you would like to participate in this discussion and join our group, please contact myself or my co-lead Weifeng Xu.



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    Lynn Kamen
    Scientific Officer, Executive Director
    BioAgilytix Labs
    Durham NC
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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  • 2.  RE: Strategies for optimizing Neutralizing Antibody Assays

    Community Leadership
    Posted 02-22-2023 09:30

    Thanks Lynn! Here is the linker for the paper that we are going to discuss: https://rdcu.be/c4brb



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    Weifeng Xu
    Director
    Merck
    West Point PA
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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  • 3.  RE: Strategies for optimizing Neutralizing Antibody Assays

    Posted 02-27-2023 07:29

    Hi Lynn, 

    I would like to participate. Please count me in. 
    Thanks,

    Seema 



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    Seema Kumar Ph.D.
    Director, Head of Clinical Bioanalytical Sciences
    EMD Serono, a business of Merck KGaA, Germany
    Billerica MA
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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  • 4.  RE: Strategies for optimizing Neutralizing Antibody Assays

    Posted 02-23-2023 18:00

    Hi Lynn,

    I am interested in participating in the discussion.

    Kind regards,



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    [Gwendolyn] [Wise-Blackman] [PhD]
    [Consultant]
    [Gwen Wise-Blackman Consulting]
    [Morrisville] [NC]
    [[email protected]]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
    ------------------------------



  • 5.  RE: Strategies for optimizing Neutralizing Antibody Assays

    Posted 02-24-2023 14:29

    Hi Lynn,

     

    Please include me in the discussion.

     

    Thanks,

     

    Henry

    GSK monitors email communications sent to and from GSK in order to protect GSK, our employees, customers, suppliers and business partners, from cyber threats and loss of GSK Information. GSK monitoring is conducted with appropriate confidentiality controls and in accordance with local laws and after appropriate consultation.






  • 6.  RE: Strategies for optimizing Neutralizing Antibody Assays

    Community Leadership
    Posted 02-27-2023 13:45

    Hi Lynn,

    Thanks for the information. I am happy to participate in the discussion.

    Best regards,

    Mark



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    Mark Ma Ph.D.
    Exe. Director
    Alexion Pharma
    New Haven CT
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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  • 7.  RE: Strategies for optimizing Neutralizing Antibody Assays

    Posted 02-28-2023 09:09

    Thanks for creating this discussion Lynn and Weifeng! Can I please be included?

    Best,



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    Rachel Wang, Ph.D.

    Bioanalytic Assay Development Lead

    Spark Therapeutics

    Philadelphia, PA

    [email protected]



  • 8.  RE: Strategies for optimizing Neutralizing Antibody Assays

    Posted 03-01-2023 09:06

    It's getting crowded in here, but please add my name to the NAb discussion group

    John Kamerud

    Pfizer



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    John Kamerud Ph.D.
    Director
    Pfizer Inc
    Andover MA
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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  • 9.  RE: Strategies for optimizing Neutralizing Antibody Assays

    Posted 03-02-2023 12:13

    Hello Lynn and all,

    Thank you for the discussion notice. I would also appreciate the chance to be included in the discussion to learn more. 

    Thanks,

    Andrew



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    Andrew Asberry
    Senior Scientist
    Sanofi
    Cambridge MA
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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  • 10.  RE: Strategies for optimizing Neutralizing Antibody Assays

    Posted 03-02-2023 12:13

    Hello Lynn,

    Please add me to the discussion as well!

    Thank you!



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    Deepkamal Karelia
    Bioanalytical Scientist
    Spark Therapeutics
    Malvern PA
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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  • 11.  RE: Strategies for optimizing Neutralizing Antibody Assays

    Community Leadership
    Posted 03-03-2023 08:26

    Hi Lynn, Weifeng,

    I'd love to join this discussion. We've been working on a method where we've applied SPEAD for a similar purpose.

    Thanks,
    Rob

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    Robert Nelson
    Scientific Director
    Labcorp Drug Development Scientific Affairs
    Meyrin, Switzerland
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer or other entities to which I am affiliated.
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  • 12.  RE: Strategies for optimizing Neutralizing Antibody Assays

    Posted 03-07-2023 08:58

    Hi Lynn,

    I would like to participate as well.

    Thanks!



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    Jad Zoghbi
    Director
    Biogen
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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