Thank you, Pankajini, for bringing up this crucial topic. Patient-Centric Sampling (PCS) holds promise and benefits, but it raises concerns about the reliability and integrity of sampling, particularly when patients play a central role in ensuring such integrity. The potential drawback lies in the challenges associated with maintaining consistent and accurate sample collection procedures, as patients may introduce variability due to factors like adherence to protocols, environmental conditions, and transportation issues. This introduces uncertainties in the reliability and precision of the collected samples, emphasizing the need for careful consideration and monitoring in PCS implementations.
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Chukwunonso Nwabufo
Senior Research Associate I,
Analytical Operations,
Gilead Sciences Alberta Canada
Edmonton AB
[email protected]Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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Original Message:
Sent: 01-19-2024 16:00
From: Pankajini Mallick
Subject: Patient‐centric sampling (PCS) closer to reality?
Why have at-home and patient-centric sampling not been adopted as standard practice in clinical trials? What are the significant hurdles to overcome?
Encourage mindset shift and create new processes/workflows?
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Pankajini Mallick PhD
Principal Scientist, Preclinical Pharmacokinetics | DMPK
San Diego CA
Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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