Therapeutic Product Immunogenicity Community

Please join for an Open Scientific Discussion (OSD) hosted by the AAPS Biomarkers and Precision Medicine (BPM) and Therapeutic Protein Immunogenicity (TPI) Communities on May 14th, 12 – 1 pm ET on the following topic:

Pharmacogenomics data from patients as biomarkers of Immunogenicity to Biologics

• Can patient HLA serve as a biomarker for immunogenicity risk?
• Predictive risk vs clinical data-related HLA association and challenges encountered
• Which parameter in in silico algorithms can correlate the best to observed clinical immunogenicity?
• Application of data mining approaches to support such associations and the development of suitable ML algorithms

Discussion Leaders:

• Surendran Rajendran (BMS)
• Andres Gutierrez (Epivax)

Moderated by: Vibha Jawa (BMS), Iris Qiu (Novartis)

Organized by: Carmen Fernández-Metzler (PharmaCadence) and Karen Quadrini (Prothena Biosciences)

We start at 12:00 ET sharp. To avoid interruptions, please dial in before noon and mute yourself until Q&A starts.

(Please remain on mute unless asking questions)

When: Wednesday, May 14, 2025 12pm – 1pm ET

Where: Please join from your computer, tablet or smartphone.
https://global.gotomeeting.com/join/305789893

You can also dial in using your phone.
United States: +1 (872) 240-3412
Access Code: 305-789-893

Join from a video-conferencing room or system.
Dial in or type: 67.217.95.2 or inroomlink.goto.com
Meeting ID: 305 789 893
Or dial directly: [email protected] or 67.217.95.2##305789893

New to GoToMeeting? Get the app now and be ready when your first meeting starts:
https://global.gotomeeting.com/install/305789893

Please feel free to share with colleagues who may be interested in this topic.

Thanks,

On Behalf of The Leadership Teams of the AAPS BPM and TPI Communities

Can this discussion be recorded and shared after the event?

Please join for an Open Scientific Discussion (OSD) hosted by the AAPS Biomarkers and Precision Medicine (BPM) and Therapeutic Protein Immunogenicity (TPI) Communities on May 14th, 12 – 1 pm ET on the following topic:

Pharmacogenomics data from patients as biomarkers of Immunogenicity to Biologics

• Can patient HLA serve as a biomarker for immunogenicity risk?
• Predictive risk vs clinical data-related HLA association and challenges encountered
• Which parameter in in silico algorithms can correlate the best to observed clinical immunogenicity?
• Application of data mining approaches to support such associations and the development of suitable ML algorithms

Discussion Leaders:

• Surendran Rajendran (BMS)
• Andres Gutierrez (Epivax)

Moderated by: Vibha Jawa (BMS), Iris Qiu (Novartis)

Organized by: Carmen Fernández-Metzler (PharmaCadence) and Karen Quadrini (Prothena Biosciences)

We start at 12:00 ET sharp. To avoid interruptions, please dial in before noon and mute yourself until Q&A starts.

(Please remain on mute unless asking questions)

When: Wednesday, May 14, 2025 12pm – 1pm ET

Where: Please join from your computer, tablet or smartphone.
https://global.gotomeeting.com/join/305789893

You can also dial in using your phone.
United States: +1 (872) 240-3412
Access Code: 305-789-893

Join from a video-conferencing room or system.
Dial in or type: 67.217.95.2 or inroomlink.goto.com
Meeting ID: 305 789 893
Or dial directly: [email protected] or 67.217.95.2##305789893

New to GoToMeeting? Get the app now and be ready when your first meeting starts:
https://global.gotomeeting.com/install/305789893

Please feel free to share with colleagues who may be interested in this topic.

Thanks,

On Behalf of The Leadership Teams of the AAPS BPM and TPI Communities