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OSD 08Oct2024_Killing or not killing: Nab assay format for ADC

  • 1.  OSD 08Oct2024_Killing or not killing: Nab assay format for ADC

    Posted 09-27-2024 17:56

    Please join the AAPS Bioanalytical Community on Oct 8th@ noon EDT for an Open Scientific Discussion:

    Killing or not killing: Nab assay format for ADC

    Since the primary mechanism of action (MOA) of antibody-drug conjugates (ADCs) in vivo is to eliminate cancer cells, should a cell-killing neutralizing antibody (NAb) assay be established as the standard approach? What challenges might arise in developing a cell-killing NAb assay for ADCs, and what additional insights could such an assay offer?

    Presenter: Weifeng Xu (Merck)

    Moderator: Sanjeev Bhardwaj (Moderna)

    Have an idea for an upcoming session?

    Please contact the OSD Committee Co-Chairs, @Sanjeev Bhardwaj & @Laurelle Calliste

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    https://www.linkedin.com/events/osdforumonneutralizingantibodya7245547762249793536/

    #bioanalysis #Bioanalytical #OSD #OpenScientificDiscussions



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    Sanjeev Bhardwaj
    Moderna Therapeutics
    Cambridge, MA.
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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