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OPEN SCIENTIFIC DISCUSSION (OSD) WITH MARISA JOUBERT | INCORPORATION OF CLINICAL OBSERVATIONS INTO SETTING CLINICALLY RELEVANT SPECIFICATIONS FOR BIOLOGICS

  • 1.  OPEN SCIENTIFIC DISCUSSION (OSD) WITH MARISA JOUBERT | INCORPORATION OF CLINICAL OBSERVATIONS INTO SETTING CLINICALLY RELEVANT SPECIFICATIONS FOR BIOLOGICS

    Community Leadership
    Posted 05-07-2024 13:47

    Please join this Open Scientific Discussion (OSD) hosted by the AAPS Biopharmaceutical Product Attributes and Biological Consequences (BPABC) Community on Monday, 20th May 2024, 12 PM – 1 PM US EDT on:  

    Incorporation of clinical observations into setting clinically relevant specifications for biologics

    Speaker / Discussion Leader: Marisa Joubert, PhD (Amgen Inc.)

    Abstract: Biological relevance tools are essential to gain knowledge about attribute impact which can be used to support clinically relevant specifications.  A new data science method called the Clinical Impact of Attributes (CIA) approach will be shared that uses clinical trial information to justify clinically safe specifications.  CIA analyzes clinical trial data to determine if any correlations exist between attribute levels exposed in patients and the development of adverse events.  Several case studies of biologics that are commercial products will be shown.

    We look forward to your participation in a lively discussion on this topic!

    When: 20th May 2024, 12 PM – 1 PM US EDT 

    Where: Please join Teams meeting using link provided below from your computer, tablet or smartphone.

    <https://teams.microsoft.com/l/meetup-join/19%3ameeting_OGRjZDYyMTgtMTA3Ni00YmVlLWFjNDAtODJjM2VkMjFiMGU4%40thread.v2/0?context=%7b%22Tid%22%3a%22d7811cde-ecef-496c-8f91-a1786241b99c%22%2c%22Oid%22%3a%22da6f9c8c-317b-4a76-90c1-87ab430ab9a3%22%7d>

    Please feel free to share meeting information with your colleagues who may be interested in this discussion.

    Thank you,

    BPABC Leadership Team



    ------------------------------
    Michael Zaleski
    PhD Candidate
    University of Pennsylvania
    Philadelphia PA
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
    ------------------------------


  • 2.  RE: OPEN SCIENTIFIC DISCUSSION (OSD) WITH MARISA JOUBERT | INCORPORATION OF CLINICAL OBSERVATIONS INTO SETTING CLINICALLY RELEVANT SPECIFICATIONS FOR BIOLOGICS

    Community Leadership
    Posted 05-14-2024 15:50

    A friendly reminder - please join the BPABC community for an upcoming OSD on Monday, 20th May 2024, 12 PM – 1 PM US EDT regarding: INCORPORATION OF CLINICAL OBSERVATIONS INTO SETTING CLINICALLY RELEVANT SPECIFICATIONS FOR BIOLOGICS

    Speaker / Discussion Leader: Marisa Joubert, PhD (Amgen Inc.)

    As a primer on this topic, two relevant papers are linked below. Please note, the OSD will be on related, but not-yet-published work. 

    1. https://link.springer.com/article/10.1007/s11095-024-03678-2
    2. https://www.sciencedirect.com/science/article/pii/S0022354919306550

    We look forward to seeing you there!

    BPABC Leadership Team

    <https://teams.microsoft.com/l/meetup-join/19%3ameeting_OGRjZDYyMTgtMTA3Ni00YmVlLWFjNDAtODJjM2VkMjFiMGU4%40thread.v2/0?context=%7b%22Tid%22%3a%22d7811cde-ecef-496c-8f91-a1786241b99c%22%2c%22Oid%22%3a%22da6f9c8c-317b-4a76-90c1-87ab430ab9a3%22%7d>



    ------------------------------
    Michael Zaleski
    PhD Candidate
    University of Pennsylvania
    Philadelphia PA
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
    ------------------------------