A Non-radiometric Approach to Determine Tissue Vascular Blood Volume in Biodistribution Studies - The AAPS Journal
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| A Non-radiometric Approach to Determine Tissue Vascular Blood Volume in Biodistribution Studies - The AAPS Journal |
| The aim of this research was to develop a reliable non-radiometric method to measure the residual blood in tissue without the need for perfusion or radiometric measurements in biodistribution studies. It was found that the perfusion method not only was ineffective in removing blood from tissue, but also introduced additional variability in the determination of tissue drug exposure and was not reproducible across studies. |
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Ho-Leung Fung Ph.D., FAAPS
Editor-in-Chief
University at Buffalo
Sarasota FL
[email protected]Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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