Pharmaceutical Discovery and Preclinical Development1

Current Approaches for Predicting Human PK for Small Molecule Development Candidates: Findings from the IQ Human PK Prediction Working Group Survey - The AAPS Journal SpringerLink remove preview Current Approaches for Predicting Human PK for Small Molecule Development Candidates: Findings from the IQ Human PK Prediction Working Group Survey - The AAPS Journal Accurate prediction of human clearance (CL) and volume of distribution at steady state (Vd,ss) for small molecule drug candidates is an essential component of assessing likely efficacious dose and clinical safety margins. In 2021, the IQ Consortium Human PK Prediction Working Group undertook a survey of IQ member companies to understand the current PK prediction methods being used to estimate these parameters across the pharmaceutical industry. View this on SpringerLink >

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Ho-Leung Fung Ph.D., FAAPS
Editor-in-Chief
University at Buffalo
Buffalo NY
[email protected]

Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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