Manufacturing Science and Engineering

Process Analytical Technology (PAT) Implementation for Membrane Operations in Continuous Manufacturing of mAbs: Model-Based Control of Single-Pass Tangential Flow Ultrafiltration - The AAPS Journal SpringerLink remove preview Process Analytical Technology (PAT) Implementation for Membrane Operations in Continuous Manufacturing of mAbs: Model-Based Control of Single-Pass Tangential Flow Ultrafiltration - The AAPS Journal Control of single pass tangential flow ultrafiltration (SPTFF) is crucial for continuous manufacturing of monoclonal antibodies (mAbs). Integrating SPTFF technology into continuous manufacturing trains requires successful resolution of several challenges that arise due to the complexity of mass transfer interactions across multi-membrane configurations, the significant effect of feed material attributes and process variability on flux, and the need for advanced scheduling. View this on SpringerLink >

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Ho-Leung Fung Ph.D., FAAPS
Editor-in-Chief
University at Buffalo
Buffalo NY
[email protected]

Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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