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Joint Disposition Properties and Comprehensive Pharmacokinetic Characterization of Antibody-Drug Conjugates - The AAPS Journal SpringerLink remove preview Joint Disposition Properties and Comprehensive Pharmacokinetic Characterization of Antibody-Drug Conjugates - The AAPS Journal Antibody-drug conjugates (ADCs) comprise 3 distinct parts: a specific antibody carrier (mAb), a linker, and a cytotoxic payload. Typical pharmacokinetic (PK) characterization of ADCs remains fragmented using separate noncompartmental analyses (NCA) of individual analytes, offering little insight into the dynamic relationships among the ADC components, and the safety and efficacy implications. View this on SpringerLink >

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Ho-Leung Fung Ph.D., FAAPS
Editor-in-Chief
University at Buffalo
Buffalo NY
[email protected]

Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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