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Mouse Brain Map and Its Relevance to CNS Research

  • 1.  Mouse Brain Map and Its Relevance to CNS Research

    Community Leadership
    Posted 04-16-2025 18:04
    The recent MICrONS project publication in Nature presents a detailed map of the mouse visual cortex, combining structural data with in vivo functional imaging from approximately 75,000 neurons. This dataset supported the construction of a "digital twin" of the brain region, aimed at improving understanding of functional level. 
    CNS indications are broad, but a common challenge remains: translating findings from preclinical models to clinical outcomes.
    I'm interested in hearing from others working in CNS areas-whatever the indication:
    - Do you see this type of data influencing your research approach?
    - Could these methods help address translational gaps in your work?
     
    Appreciate any insights or experiences you'd be open to sharing.
    The MICrONS Project
    Nature remove preview
    The MICrONS Project
    An unprecedented dataset of high resolution anatomical images of individual cells in mouse visual cortex, mapped on to their responses. This integrated view of function and structure lays a foundation for discovering the computational bases of cortical circuits.
    View this on Nature >


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    Pankajini Mallick Ph.D.
    Sr. Principal Scientist, Preclinical Pharmacokinetics | Modeling and Simulation
    San Diego CA


    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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