Therapeutic Product Immunogenicity Community

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  • 1.  MAPPS assay data analysis and data presentation

    Community Leadership
    Posted 01-25-2023 16:20
    Hi All,

    I wanted to ask the community for recommendations on how to analyze MAPPS data, an in particular whether people put weight on the intensity of the peptide peaks as a measure to quantitate the peptide. Do people normalize vs endogenous proteins / housekeeping proteins like we do for western blots? 

    Second I am looking what software solutions people use to display this data. project it on the protein sequence? heat maps ? others?

    Thanks,

    -Jochem

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    Jochem Gokemeijer
    Director
    Bristol-Myer Squibb R&D CO
    Cambridge MA
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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  • 2.  RE: MAPPS assay data analysis and data presentation

    Posted 02-02-2023 15:58

    Jochem,

    I have some thoughts on the topic, but am fairly new to MAPPs data interpretation. This could be a great near term topic to be covered in the IRAM meeting. I will propose it to Sophie for consideration. 

    Dan



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    Daniel Leventhal
    Associate Director
    Generate Biomedicines
    Somerville MA
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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