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OSD: Low Blood Volume Alternatives for Immune Monitoring in Clinical Trials

  • 1.  OSD: Low Blood Volume Alternatives for Immune Monitoring in Clinical Trials

    Community Leadership
    Posted 09-23-2025 12:58
      |   view attached
    Please join us for an Open Scientific Discussion (OSD) hosted by the AAPS Gene and Cell
    Therapy Products (GCTPs) Community on October 14, 2025, 12 pm – 1 pm EDT on the following
    topic:
    Low Blood Volume Alternatives for Immune Monitoring in Clinical Trials
    Low-volume blood collection methods are transforming immune monitoring by reducing patient
    burden and enabling more frequent, longitudinal sampling.
    Join our excellent panel of speakers/discussion leaders to engage on the following topics:
    • Shivshankar Balasubramaniam (ImmunitasBio): Low Blood Volume Alternative for Monitoring COVID-Specific T-Cell Immunity
    • Kirk Hofman ( SUNY Buffalo): An Accessible Truculture based Whole-Blood Assay for CAR-T Recall Response: Simplified Workflow with Multiplexed Immunological Readouts
    • Yanshan Dai (Avantia Labs): RT-ddPCR-based Cellular Immunity Assessment
     
    The Whole-Blood CAR-T Recall Assay offers a simplified workflow with multiplexed readouts for real-time CAR-T monitoring, while the Low-Volume COVID T-Cell Test tracks protective immunity from just a minimal blood draw, ensuring reliable and accessible insights. Complementing these approaches, the RT-ddPCR Immunity Platform delivers transcript-level precision with ultra-sensitive and reproducible detection of immune activation. Together, these innovations make immune monitoring in clinical trials more practical, scalable, and patient-friendly.
     
    Discussion Leaders:
    Vibha Jawa (Epivax Inc.)
     
    Organized by:  
    Yan Ni (Passage Bio), Yanmei Lu (Sangamo Therapeutics), Dale Miles (Genentech)
     
    We start at 12:00 PM EDT sharp. To avoid interruptions, please dial in before noon and mute
    yourself until Q&A starts.
    (Please remain on mute unless asking questions)
     
    When: October 14, 2025; 12:00pm – 1:00 pm EDT
    Where: Please join from your computer, tablet or smartphone using Microsoft Teams at this
    LINK or use the meeting ID and passcode.
     
    Meeting ID: 252 931 396 163 8
    Passcode: eK9AT3bP
    Please feel free to share with colleagues who may be interested in this topic.
     
     Thank you,
    The Leadership Teams of the AAPS BPM and GCTPs Communities



    ------------------------------
    Dale Miles
    Distinguished Scientist, Clinical Pharmacology
    Genentech
    South San Francisco CA
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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