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ICH proposing M15: Model-Informed Drug Development General Principles Guideline

  • 1.  ICH proposing M15: Model-Informed Drug Development General Principles Guideline

    Posted 11-14-2024 20:25

    The ICH Management Committee on 10Nov2024 approved a proposal for M15: Model-Informed Drug Development General Principles Guideline. 

    It is expected to take 3 years to accomplish and the draft guideline is proposed to cover:

    "The new overarching ICH M15 MIDD General Principles Guideline will broadly cover the
    general principles and good practices for the use of MIDD. The guideline will establish a
    common understanding across multidisciplinary scientists, both within and between regulatory
    authorities and industry. Additionally, the guideline will harmonize expectations regarding
    documentation standards, model development, data used in analysis, model assessment and its
    applications."

    The draft guideline is available here:

    https://database.ich.org/sites/default/files/ICH_M15_ConceptPaper_Final_2022_1102.pdf

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     #ICH #MIDD 

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    Mark Arnold Ph.D., FAAPS
    Westampton, NJ
    [email protected]
    Bioanalytical Solution Integration
    LinkedIn: https://www.linkedin.com/in/markearnoldphd/
    Website & Blog: Bioanalysis & Biomarkers <bioanalysisandbiomarkers.blogspot.com>
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