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  • 1.  FDA Updates Bioresearch Monitoring Program to include GLP in vitro tests

    Posted 06-02-2025 08:44

    Last week the FDA updated its Compliance monitoring program Chapter 48 – Bioresearch Monitoring to include 'in vitro' GLP tests (see p25 in the linked document).  Whether this is related to the Agency's plans for implementing Novel Alternative Methodologies to replace animal safety testing in coming years remains to be seen. 

    #fda #NAM #GLP #InVitro

    https://www.fda.gov/media/75891/download

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    Mark Arnold Ph.D., FAAPS
    Westampton, NJ
    [email protected]
    Bioanalytical Solution Integration
    LinkedIn: https://www.linkedin.com/in/markearnoldphd/
    Website & Blog: Bioanalysis & Biomarkers <bioanalysisandbiomarkers.blogspot.com>
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  • 2.  RE: FDA Updates Bioresearch Monitoring Program to include GLP in vitro tests

    Community Leadership
    Posted 06-09-2025 13:09

    I think that the first expansion will be into tissue cross-reactivity tests, which can be critical to establish MABEL. I know that some sites were already being audited, but perhaps there were facilities only performing tissue cross-reactivity that challenged the mandate to audit.



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    Joleen White Ph.D.
    AAPS 2024 Global Health Community Chair
    Bioanalytical 101 Course Development
    Senior Advisor
    BioData Solutions LLC
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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