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  • 1.  FDA Takes Action Aimed at Helping to Ensure the Safety and Effectiveness of Laboratory Developed Tests

    Posted 04-29-2024 11:03

    Today, the FDA announced the finalization of its enforcement plans (LINK) for lab developed tests (LDT) with a final rule which will publish on 6May2024. The unpublished rule is available here: https://public-inspection.federalregister.gov/2024-08935.pdf

    The announcement also includes links to two draft guidances related to health emergencies and the rule enforcement for LDTs.

    The impact on clinical trials and in general on patient care remains to be determined.

    #fda #LDT #enforcement

    UPDATE:
    The FDA is also hosting a webinar "Final Rule: Medical Devices; Laboratory Developed Tests" (https://www.fda.gov/medical-devices/medical-devices-news-and-events/webinar-final-rule-medical-devices-laboratory-developed-tests-05142024?utm_medium=email&utm_source=govdelivery)
    Registration is not necessary.
    Date: May 14, 2024
    Time: 1:00 PM – 2:00 PM


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    Mark Arnold Ph.D., FAAPS
    Westampton, NJ
    [email protected]
    Bioanalytical Solution Integration
    LinkedIn: https://www.linkedin.com/in/markearnoldphd/
    Website & Blog: Bioanalysis & Biomarkers <bioanalysisandbiomarkers.blogspot.com>
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    </bioanalysisandbiomarkers.blogspot.com>



  • 2.  RE: FDA Takes Action Aimed at Helping to Ensure the Safety and Effectiveness of Laboratory Developed Tests

    Community Leadership
    Posted 05-08-2024 13:02

    The Association for Diagnostics and Laboratory Medicine (ADLM, previously AACC), advocated very strongly against this change. If people are interested, there are active discussions in the Artery, their online discussion forum for members.



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    Joleen White Ph.D.
    AAPS 2024 Global Health Community Chair
    Bioanalytical 101 Course Development
    Senior Bioassay Development Lead
    Gates Medical Research Institute
    Cambridge MA
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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  • 3.  RE: FDA Takes Action Aimed at Helping to Ensure the Safety and Effectiveness of Laboratory Developed Tests

    Posted 05-10-2024 11:11

    The College of American Pathologists (CAP) is also hosting a 1-hour discussion on this rule on May 23 at 11 AM ET/10 AM CT. 
    Panelists will discuss:

    ·    Overview of the final rule
    ·    Timeline for implementation
    ·    CAP's recommendations adopted in final rule
    ·    CAP's LDT legislative advocacy efforts going forward
    ·    Q & A

    https://www.cap.org/laboratory-improvement/regulatory-updates



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    Mark Arnold Ph.D., FAAPS
    Westampton, NJ
    [email protected]
    Bioanalytical Solution Integration
    LinkedIn: https://www.linkedin.com/in/markearnoldphd/
    Website & Blog: Bioanalysis & Biomarkers <bioanalysisandbiomarkers.blogspot.com>
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