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  • 1.  EMA has released for public consultation ICH "E21 Guideline on inclusion of pregnant and breastfeeding individuals in clinical trials"

    Posted 06-04-2025 16:55

    This draft ICH guideline is open for consultation with a deadline of 15Sep25.

     

    From the guideline's Objective:

    "The objective of this guideline is to provide recommendations for the appropriate inclusion and/or retention of pregnant and/or breastfeeding individuals in clinical trials and facilitate the generation of robust clinical data that allow for evidence-based decision making on the safe and effective use of medicinal products by these individuals and their healthcare providers (HCPs)."

     

    Having worked on a few of these trials, it is an interesting read to compare with those practices.

     

    Details on the format of responses and where to send are included in the draft guideline: https://www.ema.europa.eu/en/documents/other/ich-e21-guideline-inclusion-pregnant-breastfeeding-individuals-clinical-trials_en.pdf 

    #ICH #E21 #EMA #pregnantwomen #breastfeeding #clinicaltrial



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    Mark Arnold Ph.D., FAAPS
    Westampton, NJ
    [email protected]
    Bioanalytical Solution Integration
    LinkedIn: https://www.linkedin.com/in/markearnoldphd/
    Website & Blog: Bioanalysis & Biomarkers <bioanalysisandbiomarkers.blogspot.com>
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    </bioanalysisandbiomarkers.blogspot.com>


  • 2.  RE: EMA has released for public consultation ICH "E21 Guideline on inclusion of pregnant and breastfeeding individuals in clinical trials"

    Posted 06-13-2025 07:41

    ICH just posted a powerpoint presentation with insights into the E21 draft guideline: https://admin.ich.org/sites/default/files/inline-files/ICH_Step_2_Presentation_E21_EWG_Guideline_2025_0603.pdf



    ------------------------------
    Mark Arnold Ph.D., FAAPS
    Westampton, NJ
    [email protected]
    Bioanalytical Solution Integration
    LinkedIn: https://www.linkedin.com/in/markearnoldphd/
    Website & Blog: Bioanalysis & Biomarkers <bioanalysisandbiomarkers.blogspot.com>
    ------------------------------