Oral Biopharmaceutics and Absorption Modeling Community

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  • 1.  CRO recommendation for Rat Intestinal Perfusion Model Appreciated

    Past President
    Posted 06-16-2024 14:37

    Hi All

    I am in need for a CRO that has the Rat Intestinal Perfusion Model up and running for a project. Disappearance from the lumen will do, mesenteric blood collection not needed.

    All the CROs I knew back then who did the model has stopped and googling only gives research papers

    Your help much appreciated

    Best Annette



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    Annette Bak Ph.D., MBA, FAAPS
    Executive Director
    AstraZeneca
    Weston MA
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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  • 2.  RE: CRO recommendation for Rat Intestinal Perfusion Model Appreciated

    Posted 06-17-2024 22:06
    Hi Annette,
    Not sure if this helps or not. Tried GeminiAdvanced and ChatGPT. This CRO was common to both. They are also one and the same too. Some where to start?
    Below is exactly what GeminiAdvance shared. 

    Given your urgent need for a CRO with an established Rat Intestinal Perfusion Model, I recommend focusing on these two options:

    1. Absorption Systems: This CRO specializes in drug absorption and bioavailability, making them a prime candidate. Their website explicitly highlights their expertise in rat intestinal perfusion models, indicating they have the necessary infrastructure and experience readily available.

    2. Pharmaron: As a large global CRO, Pharmaron likely has the resources and established workflows to accommodate your project quickly. Their website lists the rat intestinal perfusion model as part of their DMPK services, suggesting it's an established offering.

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    Tsung Tan
    Drug Delivery and Infusion Department Manager
    Primetech Corporation
    Tokyo
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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    Original Message


  • 3.  RE: CRO recommendation for Rat Intestinal Perfusion Model Appreciated

    Posted 06-18-2024 07:56

    Dear Annette,

    if it can be of help, at Evotec we run HPV models.

    Best regards

    Annalisa



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    Annalisa Mercuri PhD
    Research Expert
    Aptuit (Verona) S.R.L., An Evotec Company
    Verona
    [email protected]

    Disclaimer: Opinions expressed are solely my own and do not express the views or opinions of my employer.
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    Original Message