Pharmacokinetics, Pharmacodynamics, & Drug Metabolism Community

A reminder to everyone that the deadline for Programming Proposals for 2026 AAPS NBC is quickly approaching on Sep 26th.  See the announcement here: NBC - American Association of Pharmaceutical Scientists

As part of the Scientific Programming Committee leading "Track 1: Applying Translational Principles Across the Development Lifecycle" along with @Amritangshu Chakravarty, @Swetha Thiyagarajan, and @Joleen White, we would like to invite you to submit your programming proposals. Some focus areas of particular relevance to this group are:

• organoid, in silico models, in vitro models, and New Approach Methodologies (NAMs)
• AI-informed and genetic-driven target selection
• how to reach previously undruggable targets
• high-content sample analysis such as high resolution mass spectrometry (HRMS)
• new biomarker identification including omics approaches
• reverse translation to validate preclinical models
• PK/PD, PBPK, and QSP models
• challenges accounting for variability in small data sets including Phase 1 and rare diseases
• how to include women of child-bearing potential in trials
• AI and machine learning in trial design
• selection of patient population likely to respond
• evaluating clinical risks from immunogenicity seroconversion
• integrating data across multiple patient populations
• building initial exposure/response models
• clinical pharmacology such as drug-drug interactions
• clinical validation of biomarkers including companion diagnostics
• post-marketing surveillance
• regulatory review of mechanistic data
• validation of prognostic biomarkers and covariates that modulate response
• prediction of patient response to different medication options
• expansion to new indications
• recognizing successes in work involving novel modalities

Please reach out with any questions! Looking forward to an amazing conference in San Diego next year

The AAPS National Biotechnology Conference is a great opportunity to highlight innovative work in new modalities.

PPDM encourages members to submit proposals for sessions, Rapid Fire talks, or posters. Have an idea but need collaborators or speaker suggestions? Reach out we're here to help refine your concept and connect you with the right people.

Thanks Babak Basiri to for sharing this opportunity! Let's bring forward exciting science at NBC.

A reminder to everyone that the deadline for Programming Proposals for 2026 AAPS NBC is quickly approaching on Sep 26th.  See the announcement here: NBC - American Association of Pharmaceutical Scientists

As part of the Scientific Programming Committee leading "Track 1: Applying Translational Principles Across the Development Lifecycle" along with @Amritangshu Chakravarty, @Swetha Thiyagarajan, and @Joleen White, we would like to invite you to submit your programming proposals. Some focus areas of particular relevance to this group are:

• organoid, in silico models, in vitro models, and New Approach Methodologies (NAMs)
• AI-informed and genetic-driven target selection
• how to reach previously undruggable targets
• high-content sample analysis such as high resolution mass spectrometry (HRMS)
• new biomarker identification including omics approaches
• reverse translation to validate preclinical models
• PK/PD, PBPK, and QSP models
• challenges accounting for variability in small data sets including Phase 1 and rare diseases
• how to include women of child-bearing potential in trials
• AI and machine learning in trial design
• selection of patient population likely to respond
• evaluating clinical risks from immunogenicity seroconversion
• integrating data across multiple patient populations
• building initial exposure/response models
• clinical pharmacology such as drug-drug interactions
• clinical validation of biomarkers including companion diagnostics
• post-marketing surveillance
• regulatory review of mechanistic data
• validation of prognostic biomarkers and covariates that modulate response
• prediction of patient response to different medication options
• expansion to new indications
• recognizing successes in work involving novel modalities

Please reach out with any questions! Looking forward to an amazing conference in San Diego next year