Pharmacokinetics, Pharmacodynamics, & Drug Metabolism Community

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Leadership

Chair: Chukwunonso Nwabufo | Vice Chair: Pankajini Mallick | Past Chair: Abhisheak Sharma | Secretary: Jong Bong Lee | Learning Opportunities Managers: Robert "Rusty" Arnold, Michelle Kuntz, Yurong Lai, , Sejal Sharma, Jiawei Wang, Yuqing Yang | Member Engagement Managers: Saugat Adhikari, Yi-Hua Chiang, Rakesh Gollen, Sumanta Goswami, Md Masud Parvez, Kanumuri Raju, Alexandria Senetra

Community email address: [email protected]

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Latest Discussion Posts

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Announcements

  • MIDD-PBPK Webinar Organizing by AAPS-PPDM community

    Please join our AAPS PPDM community webinar. We will have two exciting talks (What “Model Master File” (MMF) Is NOT all About! and M&S Facilitating Organ Impairment Clinical Trials)

    by Amin Rostami-Hodjegan from Certara and Christine Bowman, Weize Huang, PharmD PhD from Genentech.

    Date: August 20 (12.30-2.00 PM ETD) 
    registration link: https://lnkd.in/gat3g6Am
    Moderator: Masud Parvez (AbbVie) and YiHua (University of Florida)

    More
  • JUNE 12 - Cell Therapy: Leukopaks and PBMCs

     

    Cell therapy, a transformative branch of medical science, represents a paradigm shift in the treatment of diseases by harnessing the intrinsic power of cells to restore health and combat various ailments. Leukopaks and peripheral blood mononuclear cells (PBMCs), two indispensable components that propel the field forward. Leukopaks, are harvested through advanced apheresis techniques, epitomize the pinnacle of cellular enrichment, serving as reservoirs teeming with a diverse array of immune cells crucial for therapeutic interventions. These enriched collections of white blood cells, comprising lymphocytes, monocytes, and other vital cellular constituents, stand as veritable treasure troves for researchers and clinicians alike, offering unparalleled insights into the intricate mechanisms underlying immune responses and disease pathogenesis. PBMCs, a subset of leukocytes derived from peripheral blood, embody the versatility and adaptability inherent to cellular therapies, serving as versatile tools across a spectrum of applications. From the development of cutting-edge immunotherapies targeting cancer to the growing field of regenerative medicine aimed at tissue repair and organ transplantation, the applications of PBMCs offer promising novel avenues for disease intervention and personalized medicine. As the frontier of cell therapy continues to expand, propelled by groundbreaking discoveries and technological innovations, the profound impact of leukopaks and PBMCs in shaping the future of medicine illuminating the path towards a future where diseases once deemed incurable may be conquered, and where the promise of personalized, precision medicine becomes a tangible reality for patients worldwide.

     

    Learning Objectives:

    • Understand the process of acquiring leukopaks through apheresis procedures and explain their significance in cell therapy.
    • Understand the role of peripheral blood mononuclear cells (PBMCs) in research and clinical applications within the field of cell therapy, including their versatility and potential therapeutic uses.
    • Understand the impact of leukopaks and PBMCs on advancing innovations in cancer immunotherapy and regenerative medicine, and their potential for improving patient outcomes in various disease contexts.
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  • Webinar Invitation: Developing Your Personal Board of Directors for Career Advancement

    Dear Colleagues,

    I hope this message finds you well. I am excited to announce the registration opening for our upcoming webinar: "Developing Your Personal Board of Directors for Career Advancement."

    Date and Time: 11th April 2024 at 12:30 pm ET

    Registration Link: https://lnkd.in/e68bc_dr

    This webinar aims to discuss strategies for building and sustaining an impactful board of directors that can contribute to our career progression. Your involvement and active participation as AAPS members are vital for the success of this event.

    Please feel free to pass along the registration link to your contacts who might benefit from this webinar. Let's collaborate to increase awareness about the importance of having a personal board of directors for advancing our careers.

    I appreciate your support and look forward to your participation in this enriching session.

    Best regards,

    Chuk

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  • Webinar Invitation: High-Content Modeling of Human Tissues and Diseases in vitro for Precision Drug

    Dear Colleagues,

    I hope this message finds you well. I am excited to announce the registration opening for our upcoming webinar: "High-Content Modeling of Human Tissues and Diseases in vitro for Precision Drug Screening."

    Date and Time: 5th March 2024 at 12:30 pm ET

    Registration Link: https://learning.aaps.org/topclass/topclass.do?expand-OfferingDetails-Offeringid=185775

    This webinar will explore the latest trends in utilizing microphysiological systems for precision drug discovery, providing valuable insights into advancements in the field. As members of AAPS, your engagement and participation are crucial to making this event a success.

    Please feel free to share the above registration link with your connections who may find this webinar insightful. Together, let's spread the word about the opportunities for precision medicine in drug development.

    I appreciate your support and look forward to your participation in this enriching session.

    Best regards,

    Chukwunonso Nwabufo, MSc, MBA, PhD(c)

    Chair, AAPS Pharmacokinetic, Pharmacodynamic, and Drug Metabolism Community

    More

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