Cell therapy, a transformative branch of medical science, represents a paradigm shift in the treatment of diseases by harnessing the intrinsic power of cells to restore health and combat various ailments. Leukopaks and peripheral blood mononuclear cells (PBMCs), two indispensable components that propel the field forward. Leukopaks, are harvested through advanced apheresis techniques, epitomize the pinnacle of cellular enrichment, serving as reservoirs teeming with a diverse array of immune cells crucial for therapeutic interventions. These enriched collections of white blood cells, comprising lymphocytes, monocytes, and other vital cellular constituents, stand as veritable treasure troves for researchers and clinicians alike, offering unparalleled insights into the intricate mechanisms underlying immune responses and disease pathogenesis. PBMCs, a subset of leukocytes derived from peripheral blood, embody the versatility and adaptability inherent to cellular therapies, serving as versatile tools across a spectrum of applications. From the development of cutting-edge immunotherapies targeting cancer to the growing field of regenerative medicine aimed at tissue repair and organ transplantation, the applications of PBMCs offer promising novel avenues for disease intervention and personalized medicine. As the frontier of cell therapy continues to expand, propelled by groundbreaking discoveries and technological innovations, the profound impact of leukopaks and PBMCs in shaping the future of medicine illuminating the path towards a future where diseases once deemed incurable may be conquered, and where the promise of personalized, precision medicine becomes a tangible reality for patients worldwide.

Learning Objectives:

• Understand the process of acquiring leukopaks through apheresis procedures and explain their significance in cell therapy.
• Understand the role of peripheral blood mononuclear cells (PBMCs) in research and clinical applications within the field of cell therapy, including their versatility and potential therapeutic uses.
• Understand the impact of leukopaks and PBMCs on advancing innovations in cancer immunotherapy and regenerative medicine, and their potential for improving patient outcomes in various disease contexts.

Dear Colleagues,

I hope this message finds you well. I am excited to announce the registration opening for our upcoming webinar: "Developing Your Personal Board of Directors for Career Advancement."

Date and Time: 11^th April 2024 at 12:30 pm ET

Registration Link: https://lnkd.in/e68bc_dr

This webinar aims to discuss strategies for building and sustaining an impactful board of directors that can contribute to our career progression. Your involvement and active participation as AAPS members are vital for the success of this event.

Please feel free to pass along the registration link to your contacts who might benefit from this webinar. Let's collaborate to increase awareness about the importance of having a personal board of directors for advancing our careers.

I appreciate your support and look forward to your participation in this enriching session.

Best regards,

Chuk

Dear Colleagues,

I hope this message finds you well. I am excited to announce the registration opening for our upcoming webinar: "High-Content Modeling of Human Tissues and Diseases in vitro for Precision Drug Screening."

Date and Time: 5^th March 2024 at 12:30 pm ET

Registration Link: https://learning.aaps.org/topclass/topclass.do?expand-OfferingDetails-Offeringid=185775

This webinar will explore the latest trends in utilizing microphysiological systems for precision drug discovery, providing valuable insights into advancements in the field. As members of AAPS, your engagement and participation are crucial to making this event a success.

Please feel free to share the above registration link with your connections who may find this webinar insightful. Together, let's spread the word about the opportunities for precision medicine in drug development.

I appreciate your support and look forward to your participation in this enriching session.

Best regards,

Chukwunonso Nwabufo, MSc, MBA, PhD(c)

Chair, AAPS Pharmacokinetic, Pharmacodynamic, and Drug Metabolism Community

Dear PPDM Community Members,

I trust this message finds you well. In our continuous pursuit of knowledge and collaboration, we are thrilled to announce the establishment of a Scientific Contribution Subcommittee aimed at writing and publishing focused white papers on a select aspect of PPDM.

Why Join?

By joining the Scientific Contribution Subcommittee, you will not only be at the forefront of shaping the narrative within our field but also play a crucial role in driving meaningful discussions and insights. One of the exciting aspects of this initiative is the potential for your contributions to be published. The white paper resulting from our collective efforts will provide a platform for showcasing your expertise and insights to a broader audience, both within our community and beyond. This aligns with our overarching themes of Innovate, Excel, and Inspire

Key Responsibilities:

• Collaborate with fellow subcommittee members to identify and define the specific aspect of PPDM to be addressed in the white paper.
• Conduct thorough research and analysis on the chosen topic.
• Contribute to the writing and review process, ensuring the white paper reflects the highest standards of quality and relevance.
• Participate in regular meetings to discuss progress, share insights, and coordinate efforts with other subcommittee members.

Time Commitment:

Active participation in the Scientific Contribution Subcommittee is estimated to require approximately 5 hours per week writing the paper and 1-hour biweekly progress meeting (or as the subcommittee deems adequate to achieve desired success in real time) .

Express Your Interest:

If you are passionate about making a meaningful contribution to the development and advancement of PPDM knowledge and wish to be a part of this exciting initiative, please respond to this email no later than 5 pm ET on November 17th, 2023.

Your dedication and expertise are invaluable to the success of this endeavor, and we look forward to collaboratively driving innovation, excelling in knowledge, and inspiring through publication within our vibrant PPDM community.

Thank you for your ongoing support.

Best regards,

Chuk