AAPS-LBDDS Webinar Invitation
(Jointly hosted by LBDDS, Nanotech and Modified Release Communities)
Hydrophobic Ion Pairing in Self-emulsifying System: Drug Loading and Precipitation Kinetics
Dr. Ketan Patel, Associate Professor of Pharmaceutical Sciences, St. John’s University, New York, NY.
Self-nanoemulsifying system is one of the simplest yet versatile drug delivery platforms for lipophilic drug molecules. In pursuit of developing molecules targeting “undruggable” proteins, the majority of the novel class of anticancer molecules are poorly water-soluble molecules falling in the Extended rule of 5 (ERo5) or Extended rule of 5 (BRo5) space. Poor drug loading in self-emulsifying preconcentrate and rapid precipitation in contact with an aqueous milieu are the key factors limiting the translational potential of lipid-based systems. The webinar will cover the current challenges in lipid-based drug delivery systems and the role of the hydrophobic ion pairing approach in enhancing drug loading as well as minimizing precipitation in the aqueous phase.
August 08, 2024, 12:00 to 1:30 pm Eastern Time (US and Canada)
Register: https://learning.aaps.org/topclass/topclass.do?expand-OfferingDetails-Offeringid=310654